Thursday, January 7, 2010

Pharmaceutical Calculations, Ansel And Stocklosa Hi, I'm Having Some Tough Time Trying To Understand Some QA Calculations For Pharmaceutical Products.?

Hi, I'm having some tough time trying to understand some QA calculations for pharmaceutical products.? - pharmaceutical calculations, ansel and stocklosa

This is a test of content uniformity of drug-ABC.

Standard Preparation
Weigh the reference samples mg and the amount of the ABC and with water to 100 ml in a volumetric flask. Pipette 5 ml of solution and replenish ml to 100.

Sample
ABC just 1 tablet in a volumetric flask. Dissolved in a solvent, ml to 100. Filter and store 1 10 ml of the filtrate. Dilute 25 ml of clear filtrate to 50ml.

Procedure:
The absorption was using a spectrophotometer.
% ABC =

At x Y x 5 mg x 100 x 50 x 100 x% purity Std
---------------------------------------- ...
As 100 100 25 2 100

Au - absorbance of sample solution
As - absorbance of standard solution
Please can someone explain how to obtain this type of training?

Thank you ... pls no spam.

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